A large part of what makes the DGR risky is that this has never been done before. We don’t know what we’re up against. But we do know that there are some particular areas of concern – such as public health – where it is imperative to explore the risks in detail and consider whether suitable preventative measures and backup plans can be implemented to make the risk worth taking. Unfortunately, much of the research that would be needed to better evaluate these risks has not been done.